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Literature summary for 1.2.3.1 extracted from

  • Obach, R.S.; Huynh, P.; Allen, M.C.; Beedham, C.
    Human liver aldehyde oxidase: inhibition by 239 drugs (2004), J. Clin. Pharmacol., 44, 7-19.
    View publication on PubMed
Search for more literature for 1.2.3.1

Inhibitors

Inhibitors Comment Organism Structure
amitriptyline 0.00026 mM, 50% inhibition Homo sapiens
amlodipine 0.0055 mM, 50% inhibition Homo sapiens
amodiaquine 0.00074 mM, 50% inhibition Homo sapiens
chlorpromazine 0.00057 mM, 50% inhibition Homo sapiens
clomipramine 0.00048 mM, 50% inhibition Homo sapiens
clozapine 0.0044 mM, 50% inhibition Homo sapiens
cyclobenzaprine 0.0031 mM, 50% inhibition Homo sapiens
domperidone 0.0030 mM, 50% inhibition Homo sapiens
erythromycin 0.015 mM, 50% inhibition Homo sapiens
estradiol 0.00029 mM, 50% inhibition Homo sapiens
ethinyl estradiol 0.00057 mM, 50% inhibition Homo sapiens
felodipine 0.00030 mM, 50% inhibition Homo sapiens
ketoconazole 0.0035 mM, 50% inhibition Homo sapiens
loperamide 0.010 mM, 50% inhibition Homo sapiens
loratidine 0.00049 mM, 50% inhibition Homo sapiens
loxapine 0.0023 mM, 50% inhibition Homo sapiens
maprotiline 0.0014 mM, 50% inhibition Homo sapiens
menadione 0.00020 mM, 50% inhibition Homo sapiens
metoclopramide 0.031 mM, 50% inhibition Homo sapiens
norclomipramine 0.00060 mM, 50% inhibition Homo sapiens
nortriptyline 0.00085 mM, 50% inhibition Homo sapiens
olanzapine 0.0060 mM, 50% inhibition Homo sapiens
ondansetron 0.0021 mM, 50% inhibition Homo sapiens
perphenazine 0.00003 mM, 50% inhibition Homo sapiens
promazine 0.0016 mM, 50% inhibition Homo sapiens
Promethazine 0.00051 mM, 50% inhibition Homo sapiens
propafenone 0.0025 mM, 50% inhibition Homo sapiens
quetiapine 0.0014 mM, 50% inhibition Homo sapiens
Quinacrine 0.0033 mM, 50% inhibition Homo sapiens
raloxifene 0.000003 mM, 50% inhibition Homo sapiens
salmeterol 0.0099 mM, 50% inhibition Homo sapiens
tacrine 0.0050 mM, 50% inhibition Homo sapiens
tamoxifen 0.0022 mM, 50% inhibition Homo sapiens
thioridazine 0.00016 mM, 50% inhibition Homo sapiens
Trifluperazine 0.00024 mM, 50% inhibition Homo sapiens
verapamil 0.0035 mM, 50% inhibition Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phthalazine + O2 + H2O
-
 Homo sapiens 1-phthalazinone + H2O2
-
 ?