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Literature summary for 1.2.3.1 extracted from

  • Al-Salmy, H.S.
    Inter-strain variability in aldehyde oxidase activity in the mouse (2002), Comp. Biochem. Physiol. C, 132, 341-347.
    View publication on PubMed
Search for more literature for 1.2.3.1

Inhibitors

Inhibitors Comment Organism Structure
menadione 0.006 mM, 0.0042 mM, 0.0026 mM, 0.001 mM, 0.0014 mM and 0.0008 mM, 50% inhibition of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide oxidation in male swiss CD mouse, CB57BI/6J, female swiss CD mouse, nude mouse, nude mouse tumor bearing and C129/C57 muse, respectively Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0029
-
 N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide 37°C, pH 7.8, strain c129/C57 Mus musculus
0.0055
-
 N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide 37°C, pH 7.8, nude mouse tumor bearing Mus musculus
0.0074
-
 N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide 37°C, pH 7.8, nude mouse Mus musculus
0.027
-
 N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide 37°C, pH 7.8, female swiss CD Mus musculus
0.03
-
 N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide 37°C, pH 7.8, male swiss CD Mus musculus
0.05
-
 N-[2-(Dimethylamino)ethyl]acridine-4-carboxamide 37°C, pH 7.8, strain CB57BI/6J Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Mus musculus 5829
-

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzaldehyde + H2O + O2
-
 Mus musculus benzoate + H2O2
-
 ?
N-[2-(dimethylamino)ethyl]acridine-4-carboxamide + H2O + O2 antitumor drug Mus musculus N-[2-(dimethylamino)ethyl]acridine-4-carboxamide-9-(10H)-acridone + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
AO
-
 Mus musculus