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Literature summary for 1.2.3.1 extracted from
- Kinetic and inhibition studies on reduction of diphenyl sulfoxide by guinea pig liver aldehyde oxidase (1986), Arch. Biochem. Biophys., 249, 8-14.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| allopurinol | 45% inhibition at 0.25 mM | Cavia porcellus |  |
| beta-estradiol | 90% inhibition at 0.02 mM | Cavia porcellus | |
| diphenylsulfoxide | 85% inhibition at 0.1 mM, it serves as an inhibitor in presence of other electron acceptors | Cavia porcellus | |
| dithiothreitol | 45% and 92% inhibition at 0.1 mM and 1 mM respectively | Cavia porcellus | |
| menadione | 95% inhibition at 0.02 mM | Cavia porcellus | |
| norharman | 50% inhibition at 0.01 mM | Cavia porcellus | |
| SKF 525-A | 62% inhibition at 0.1 mM | Cavia porcellus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.002 | - |
methylene blue | as electron acceptor under aerobic conditions | Cavia porcellus | |
| 0.007 | - |
2,6-dichlorophenolindophenol | as electron acceptor under aerobic conditions | Cavia porcellus | |
| 0.02 | - |
diphenylsulfoxide | as electron acceptor under anaerobic conditions | Cavia porcellus | |
| 0.03 | - |
ferricyanide | as electron acceptor under aerobic conditions | Cavia porcellus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 300000 | - |
PAGE | Cavia porcellus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Cavia porcellus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-hydroxypyrimidine + H2O + O2 | diphenylsulfoxide as electron acceptor under anaerobic conditions | Cavia porcellus | uracil + H2O2 | - |
? | |
| benzaldehyde + 2 ferricyanide + H2O | - |
Cavia porcellus | benzoate + 2 ferrocyanide + 2 H+ | - |
? | |
| diphenyl sulfoxide + 2,6-dichlorophenolindophenol | - |
Cavia porcellus | ? | - |
r | |
| diphenyl sulfoxide + acetaldehyde + H2O | - |
Cavia porcellus | ? | - |
? | |
| diphenyl sulfoxide + methylene blue | - |
Cavia porcellus | ? | - |
r | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AO | - |
Cavia porcellus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| FAD | - |
Cavia porcellus | |
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