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Literature summary for 1.2.1.90 extracted from

  • Brunner, N.A.; Siebers, B.; Hensel R.
    Role of two different glyceraldehyde-3-phosphate dehydrogenases in controlling the reversible Embden-Meyerhof-Parnas pathway in Thermoproteus tenax: regulation on protein and transcript level (2001), Extremophiles, 5, 101-109.
    View publication on PubMed

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
D-glyceraldehyde 3-phosphate pH 7.0, 70°C Thermoproteus tenax
0.02
-
D-glyceraldehyde 3-phosphate pH 7.0, 45°C Thermoproteus tenax
1
-
NAD+ pH 7.0, 45°C Thermoproteus tenax
3.1
-
NAD+ pH 7.0, 70°C Thermoproteus tenax

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-glyceraldehyde 3-phosphate + NAD+ + H2O Thermoproteus tenax the enzyme is part of the modified Embden–Meyerhof–Parnas pathway, the main route for carbohydrate metabolism in Thermoproteus tenax 3-phospho-D-glycerate + NADH + 2 H+
-
ir

Organism

Organism UniProt Comment Textmining
Thermoproteus tenax O57693
-
-

Source Tissue

Source Tissue Comment Organism Textmining
culture condition:autotrophically-grown cell specific activity of remains constant in autotrophically and heterotrophically grown cells Thermoproteus tenax
-
culture condition:heterotrophically-grown cell specific activity of remains constant in autotrophically and heterotrophically grown cells Thermoproteus tenax
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glyceraldehyde 3-phosphate + NAD+ + H2O
-
Thermoproteus tenax 3-phospho-D-glycerate + NADH + 2 H+
-
ir
D-glyceraldehyde 3-phosphate + NAD+ + H2O the enzyme is part of the modified Embden–Meyerhof–Parnas pathway, the main route for carbohydrate metabolism in Thermoproteus tenax Thermoproteus tenax 3-phospho-D-glycerate + NADH + 2 H+
-
ir

Synonyms

Synonyms Comment Organism
GAPN
-
Thermoproteus tenax
nonphosphorylating NAD+-dependent GAPN
-
Thermoproteus tenax

General Information

General Information Comment Organism
metabolism the enzyme is part of the modified Embden–Meyerhof–Parnas pathway, the main route for carbohydrate metabolism in Thermoproteus tenax Thermoproteus tenax