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Literature summary for 1.2.1.84 extracted from
- Biochemical characterization and substrate specificity of jojoba fatty acyl-CoA reductase and jojoba wax synthase (2016), Plant Sci., 249, 84-92.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| bovine serum albumin | in vitro, addition of 0.5 mg of bovine serum albumin to the reaction mixture results in a fourfold increase of produced fatty alcohols | Simmondsia chinensis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Simmondsia chinensis | Q9XGY7 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| eicosenoyl-CoA + NADPH + H+ | about 50% of the activity with stearoyl-CoA | Simmondsia chinensis | eicosenyl alcohol + NADP+ | - |
? |  |
| erucoyl-CoA + NADPH + H+ | about 30% of the activity with stearoyl-CoA | Simmondsia chinensis | erucyl alcohol + NADP+ | - |
? | |
| stearoyl-CoA + NADPH + H+ | - |
Simmondsia chinensis | stearyl alcohol + NADP+ | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 40 | - |
- |
Simmondsia chinensis |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 25 | - |
twofold decrease in enzyme activity compared to 40°C | Simmondsia chinensis |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
- |
Simmondsia chinensis |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 4 | - |
inactive | Simmondsia chinensis |
| 7.5 | - |
42% of maximum activity | Simmondsia chinensis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Simmondsia chinensis | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | expression in yeast leads to production of mainly 18:0 and 16:0 alcohols, which account for 57% and 29% of the total fatty alcohol production respectively, while18:1-0H and 20:0-OH are formed in lower quantities | Simmondsia chinensis |
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Release 2023.1 (January 2023)
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