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Literature summary for 1.2.1.48 extracted from
- Long-chain aldehyde dehydrogenase of Candida Yeast (1990), Methods Enzymol., 188, 176-178.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Yarrowia lipolytica | - |
- |
| microsome | - |
Candida tropicalis | - |
- |
| mitochondrion | - |
Yarrowia lipolytica | 5739 | - |
| mitochondrion | - |
Candida tropicalis | 5739 | - |
| peroxisome | - |
Yarrowia lipolytica | 5777 | - |
| peroxisome | - |
Candida tropicalis | 5777 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| long-chain aldehyde + NAD+ | Yarrowia lipolytica | in microsomes and mitochondria: provides long-chain fatty acids to be utilized for lipid synthesis | ? | - |
? |  |
| long-chain aldehyde + NAD+ | Candida tropicalis | in microsomes and mitochondria: provides long-chain fatty acids to be utilized for lipid synthesis | ? | - |
? | |
| long-chain aldehyde + NAD+ | Yarrowia lipolytica | in peroxisomes: provides long-chain fatty acids to be degraded via beta-oxidation to yield energy and cell constituents | ? | - |
? | |
| long-chain aldehyde + NAD+ | Candida tropicalis | in peroxisomes: provides long-chain fatty acids to be degraded via beta-oxidation to yield energy and cell constituents | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Candida tropicalis | - |
- |
- |
| Yarrowia lipolytica | - |
- |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.00879 | - |
glucose-grown cell | Candida tropicalis |
| 0.0932 | - |
stearyl alcohol-grown cell | Candida tropicalis |
| 0.098 | - |
alkane-grown cell | Candida tropicalis |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| long-chain aldehyde + NAD+ | in microsomes and mitochondria: provides long-chain fatty acids to be utilized for lipid synthesis | Yarrowia lipolytica | ? | - |
? | |
| long-chain aldehyde + NAD+ | in microsomes and mitochondria: provides long-chain fatty acids to be utilized for lipid synthesis | Candida tropicalis | ? | - |
? | |
| long-chain aldehyde + NAD+ | in peroxisomes: provides long-chain fatty acids to be degraded via beta-oxidation to yield energy and cell constituents | Yarrowia lipolytica | ? | - |
? | |
| long-chain aldehyde + NAD+ | in peroxisomes: provides long-chain fatty acids to be degraded via beta-oxidation to yield energy and cell constituents | Candida tropicalis | ? | - |
? | |
| long-chain aldehyde + NAD+ + H2O | - |
Yarrowia lipolytica | long-chain acid anion + NADH | - |
? | |
| long-chain aldehyde + NAD+ + H2O | - |
Candida tropicalis | long-chain acid anion + NADH | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Yarrowia lipolytica | |
| NAD+ | - |
Candida tropicalis | |
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Release 2023.1 (January 2023)
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