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Literature summary for 1.2.1.36 extracted from
- Ethanol induces embryonic malformations by competing for retinaldehyde dehydrogenase activity during vertebrate gastrulation (2009), Dis. Model. Mech., 2, 295-305.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 4-diethylaminobenzaldehyde | partial inhibition | Xenopus laevis |  |
| ethanol | competitive inhibition | Xenopus laevis | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Xenopus laevis | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryo | RALDH2 activity is present in limiting levels in the early gastrula embryo | Xenopus laevis | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Aldh1a2 | - |
Xenopus laevis |
| RALDH2 | - |
Xenopus laevis |
| retinaldehyde dehydrogenase 2 | - |
Xenopus laevis |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | retinaldehyde dehydrogenase 2 is required to activate retinoic acid signaling at the onset of gastrulation | Xenopus laevis |
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Release 2023.1 (January 2023)
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