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Literature summary for 1.2.1.36 extracted from
- Regulation of RALDH-1, RALDH-3 and CYP26A1 by transcription factors cVax/Vax2 and Tbx5 in the embryonic chick retina (2008), Int. J. Dev. Neurosci., 26, 435-445.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | transfection of transcription factor cVax/Vax2 causes an ectopic expression of RALDH-3 in the dorsal retina. Transfection of transcription factor Tbx5 does not significantly alter the distribution of RALDH-3 | Gallus gallus | |
| additional information | transfection of transcription factor Tbx5 does not significantly alter the distribution of RALDH-1 | Gallus gallus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | transfection of transcription factor cVax/Vax2 completely abolishes the spatial expression pattern of the retinoic acid synthesizing enzyme RALDH-1 | Gallus gallus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | P27463 | - |
- |
| Gallus gallus | Q9DD46 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryo | - |
Gallus gallus | - |
| eye | in wild-type embryos, RALDH-3 is expressed within the developing eye vesicle in the ventral third of the retina | Gallus gallus | - |
| eye | in wild-type embryos, the distribution of Raldh-1 is limited to the dorsal third of the eye | Gallus gallus | - |
| retina | - |
Gallus gallus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| RALDH-1 | - |
Gallus gallus |
| RALDH-3 | - |
Gallus gallus |
| retinaldehyde dehydrogenase | - |
Gallus gallus |
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