Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ATP | 30% inhibition at 1 mM | Pseudomonas putida | |
carbonyl reagents | e.g.: hydroxylamine, KCN, in the presence of substrate | Pseudomonas putida | |
HSO3- | in presence of substrate | Pseudomonas putida | |
hydroxylamine | in presence of substrate | Pseudomonas putida | |
KCN | in presence of substrate | Pseudomonas putida |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.002 | - |
DELTA1-piperidine 6-carboxylate | - |
Pseudomonas putida |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no metal cofactor required | Pseudomonas putida |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-2-aminoadipate-semialdehyde + NAD+ | Pseudomonas putida | degradative enzyme | L-2-aminoadipate + NADH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas putida | - |
- |
- |
Purification (Comment) | Organism |
---|---|
using protamine sulfate treatment, ammonium sulfate fractionation and treatment with calcium phosphate gel | Pseudomonas putida |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
4.9 | - |
after purification, gel fraction | Pseudomonas putida |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-2,3,4,5-tetrahydropyridine-2-carboxylate + NAD+ + H2O | - |
Pseudomonas putida | L-2-aminoadipate + NADH | - |
ir | |
DELTA1-piperidine 6-carboxylate + NAD+ + H2O | - |
Pseudomonas putida | L-alpha-aminoadipate + NADH + H+ | - |
r | |
L-2-aminoadipate 6-semialdehyde + NAD+ + H2O | - |
Pseudomonas putida | L-2-aminoadipate + NADH | - |
ir | |
L-2-aminoadipate-semialdehyde + NAD+ | degradative enzyme | Pseudomonas putida | L-2-aminoadipate + NADH | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.1 | - |
L-alpha-aminoadipate-semialdehyde reduction | Pseudomonas putida |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Pseudomonas putida |