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Literature summary for 1.2.1.3 extracted from

  • Lin, Y.R.; Hung, H.C.; Leu, J.H.; Wang, H.C.; Kou, G.H.; Lo, C.F.
    The role of aldehyde dehydrogenase and hsp70 in suppression of white spot syndrome virus replication at high temperature (2011), J. Virol., 85, 3517-3525.
    View publication on PubMedView publication on EuropePMC

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
62400
-
x * 62400, ESI-MS Penaeus vannamei

Organism

Organism UniProt Comment Textmining
Penaeus vannamei
-
-
-

Subunits

Subunits Comment Organism
? x * 62400, ESI-MS Penaeus vannamei

pI Value

Organism Comment pI Value Maximum pI Value
Penaeus vannamei isoelectric focusing
-
5.9

General Information

General Information Comment Organism
physiological function in white spot syndrome virus- (WSSV-)infected shrimps cultured at 32°C, transcriptional levels of representative immediate-early, early, and late genes are initially higher than those at 25°C. NAD-dependent aldehyde dehydrogenase (ALDH) and the proteasome alpha 4 subunit (proteasome alpha4) are markedly upregulated in WSSV-infected shrimps at 32°C. In addition, hsp70 is upregulated at 32°C. When aldh, proteasome alpha4, and hsp70 are knocked down by double-stranded RNA interference and shrimps are challenged with WSSV, the aldh and hsp70 knockdown shrimps become severely infected at 32°C, while the proteasome alpha4 knockdown shrimps remain uninfected Penaeus vannamei