Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Chloral hydrate | competitive with aldehyde | Homo sapiens | |
Disulfiram | non-competitive | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00055 | - |
cinnamaldehyde | - |
Homo sapiens | |
0.00065 | - |
benzaldehyde | - |
Homo sapiens | |
0.015 | - |
NAD+ | - |
Homo sapiens | |
0.017 | - |
acetylaldehyde | at substrate concentrations 0-0.07 mM | Homo sapiens | |
0.18 | - |
glycolaldehyde | - |
Homo sapiens | |
0.205 | - |
glyceraldehyde | - |
Homo sapiens | |
0.765 | - |
propanal | at substrate concentrations 0.8-20 mM | Homo sapiens | |
0.83 | - |
acetaldehyde | at substrate concentrations 0.8-20 mM | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
51500 | - |
4 * 51500, SDS-PAGE | Homo sapiens |
210000 | - |
gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.462 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-20°C, 20% glycerol, less than 15% loss of activity per months | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glyceraldehyde + NAD+ + H2O | - |
Homo sapiens | glycerate + NADH | - |
? | |
glycolaldehyde + NAD+ + H2O | - |
Homo sapiens | glycolate + NADH | - |
? |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 51500, SDS-PAGE | Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | very low activity | Homo sapiens | |
NAD+ | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.17 | - |
Chloral hydrate | - |
Homo sapiens |