Inhibitors | Comment | Organism | Structure |
---|---|---|---|
4-hydroxy-trans-2-nonenal | IC50: 0.11 mM | Rattus norvegicus | |
acrolein | irreversible, noncompetitive, IC50: 0.015 mM | Rattus norvegicus | |
additional information | no inhibition by 0.1 mM trans-2-hexenal and 0.1 mM crotonaldehyde | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0039 | - |
succinate semialdehyde | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinate semialdehyde + NAD+ + H2O | - |
Rattus norvegicus | succinate + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SSADH/ALDH5A1 | - |
Rattus norvegicus |
succinic semialdehyde dehydrogenase | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.015 | - |
irreversible, noncompetitive, IC50: 0.015 mM | Rattus norvegicus | acrolein | |
0.11 | - |
IC50: 0.11 mM | Rattus norvegicus | 4-hydroxy-trans-2-nonenal |