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Literature summary for 1.2.1.21 extracted from
- Experimental evolution of a metabolic pathway for ethylene glycol utilization by Escherichia coli (1983), J. Bacteriol., 153, 134-139.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Escherichia coli | - |
grown on ethylene glycol | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.145 | - |
enzyme activity in crude extracts of wild-type strain G1 | Escherichia coli |
| 0.165 | - |
enzyme activity in crude extracts of wild-type strain G3 | Escherichia coli |
| 0.56 | - |
enzyme activity in crude extracts of ethylene glycol positive mutant strain EG3 | Escherichia coli |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glycolaldehyde + NAD+ + H2O | - |
Escherichia coli | glycolate + NADH | - |
? |  |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Escherichia coli | |
| NADP+ | 10 times lower activity compared to NAD+ | Escherichia coli | |
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Release 2023.1 (January 2023)
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