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Literature summary for 1.2.1.19 extracted from

  • Callewaert, D.M.; Rosemblatt, M.S.; Tchen, T.T.
    Purification and properties of 4-aminobutanal dehydrogenase from a Pseudomonas species (1974), J. Biol. Chem., 249, 1737-1741.
    View publication on PubMed
Search for more literature for 1.2.1.19

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
75000
-
 3 * 75000, SDS-PAGE Pseudomonas sp.
228000
-
 gel filtration, PAGE Pseudomonas sp.

Organic Solvent Stability

Organic Solvent Comment Organism
Glycerol stable in 30% with 5 mM mercaptoethanol + 5 mM EDTA Pseudomonas sp.

Organism

Organism UniProt Comment Textmining
Pseudomonas sp.
-
-
-

Purification (Commentary)

Purification (Comment) Organism
from putrescine-grown cells, using column chromatography on DEAE-cellulose, DEAE-Sephadex A-50, Sephadex G-200, Hydroxylapatite and Sephadex G-200 in 150 mM NaCl Pseudomonas sp.

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.22
-
-
 Pseudomonas sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-aminobutanal + NAD+ + H2O
-
 Pseudomonas sp. 4-aminobutanoate + NADH + H+
-
 ?
additional information very low activity with: succinate semialdehyde Pseudomonas sp. ?
-
 ?

Subunits

Subunits Comment Organism
trimer 3 * 75000, SDS-PAGE Pseudomonas sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
 3-aminopropanal Pseudomonas sp.
9 10 4-aminobutanal Pseudomonas sp.

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Pseudomonas sp.