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Literature summary for 1.2.1.12 extracted from

  • Margaryan, H.; Dorosh, A.; Capkova, J.; Manaskova-Postlerova, P.; Philimonenko, A.; Hozak, P.; Peknicova, J.
    Characterization and possible function of glyceraldehyde-3-phosphate dehydrogenase-spermatogenic protein GAPDHS in mammalian sperm (2015), Reprod. Biol. Endocrinol., 13, 15 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.12

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-glyceraldehyde 3-phosphate + phosphate + NAD+ Homo sapiens
-
 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 r
D-glyceraldehyde 3-phosphate + phosphate + NAD+ Mus musculus
-
 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 r
D-glyceraldehyde 3-phosphate + phosphate + NAD+ Mus musculus BALB/c
-
 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 r

Organism

Organism UniProt Comment Textmining
Homo sapiens O14556
-
-
Mus musculus Q64467
-
-
Mus musculus BALB/c Q64467
-
-

Source Tissue

Source Tissue Comment Organism Textmining
sperm cell ejaculated sperm cells, localization of the GAPDHS protein in the sperm head, immunologic analysis, in the principal piece and acrosomal part of the sperm cells, overview Homo sapiens
-
sperm cell epididymal spermatozoa, localization of the GAPDHS protein in the sperm head, immunologic analysis, in the principal piece and acrosomal part of the sperm cells, overview Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glyceraldehyde 3-phosphate + phosphate + NAD+
-
 Homo sapiens 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 r
D-glyceraldehyde 3-phosphate + phosphate + NAD+
-
 Mus musculus 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 r
D-glyceraldehyde 3-phosphate + phosphate + NAD+
-
 Mus musculus BALB/c 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 r

Subunits

Subunits Comment Organism
? x * 75000, about, recombinant enzyme, SDS-PAGE, x * 45000-50000, native enzyme, SDS-PAGE Homo sapiens
? x * 75000, about, recombinant enzyme, SDS-PAGE, x * 45000-50000, native enzyme, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
D-glyceraldehyde-3-phosphate dehydrogenase
-
 Mus musculus
GAPDH
-
 Mus musculus
GAPDHS
-
 Homo sapiens
glyceraldehyde-3-phosphate dehydrogenase-spermatogenic protein
-
 Homo sapiens
glyceraldehyde-3-phosphate dehydrogenase-spermatogenic protein GAPDHS
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens
NAD+
-
 Mus musculus
NADH
-
 Homo sapiens
NADH
-
 Mus musculus

General Information

General Information Comment Organism
physiological function glyceraldehyde-3-phosphate dehydrogenase-spermatogenic protein, GAPDHS, is a sperm-specific glycolytic enzyme involved in energy production during spermatogenesis and sperm motility Homo sapiens
physiological function glyceraldehyde-3-phosphate dehydrogenase-spermatogenic protein, GAPDHS, is a sperm-specific glycolytic enzyme involved in energy production during spermatogenesis and sperm motility Mus musculus