Protein Variants | Comment | Organism |
---|---|---|
A229V | exhibits 50-55% residual activity in blood compared to the wild type enzyme | Mus musculus |
C281W | exhibits 50-55% residual activity in blood compared to the wild type enzyme | Mus musculus |
G166D | exhibits 50-55% residual activity in blood compared to the wild type enzyme | Mus musculus |
I308S | exhibits 50-55% residual activity in blood compared to the wild type enzyme | Mus musculus |
additional information | mutants Gapdhm1Neu (Y91stop truncated protein of 89 amino acids), Gapdhm2Neu (truncated/altered protein of 9 amino acids), and Gapdhm8Neu (truncated/altered protein of 73 amino acids) exhibit 50-55% residual activity in blood compared to the wild type enzyme | Mus musculus |
V239I | exhibits 50-55% residual activity in blood compared to the wild type enzyme | Mus musculus |
Y327N | exhibits 50-55% residual activity in blood compared to the wild type enzyme | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
37000 | - |
4 * 37000, SDS-PAGE | Mus musculus |
150000 | - |
SDS-PAGE | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Mus musculus | - |
brain | - |
Mus musculus | - |
heart | - |
Mus musculus | - |
kidney | - |
Mus musculus | - |
liver | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
spleen | - |
Mus musculus | - |
tail | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + phosphate + NAD+ | - |
Mus musculus | 3-phospho-D-glyceroyl phosphate + NADH + H+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
homotetramer | 4 * 37000, SDS-PAGE | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
D-glyceraldehyde-3-phosphate dehydrogenase | - |
Mus musculus |
GAPDH | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | GAPDH binds four NAD+ molecules per subunit | Mus musculus |