Cloned (Comment) | Organism |
---|---|
coexpressed with P450 27A1 and adrenodoxin in Escherichia coli DH5alpha cells | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
52000 | - |
x * 52000, SDS-PAGE | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
oxidized adrenodoxin + NADPH + H+ | - |
Homo sapiens | reduced adrenodoxin + NADP+ | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 52000, SDS-PAGE | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
AdR | - |
Homo sapiens |
adrenodoxin reductase | - |
Homo sapiens |
NADPH-adrenodoxin reductase | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Homo sapiens |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is the first component in the mitochondrial P450 electron transfer systems. Coexpressed P450, adrenodoxin, and adrenodoxin reductase interact catalytically and allow Escherichia coli to oxidize both cholesterol and vitamin D3 | Homo sapiens |