Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.18.1.6 extracted from

  • Salamanca-Pinzon, S.; Guengerich, F.
    A tricistronic human adrenodoxin reductase-adrenodoxin-cytochrome P450 27A1 vector system for substrate hydroxylation in Escherichia coli (2011), Protein Expr. Purif., 79, 231-236.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
coexpressed with P450 27A1 and adrenodoxin in Escherichia coli DH5alpha cells Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
x * 52000, SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
oxidized adrenodoxin + NADPH + H+
-
Homo sapiens reduced adrenodoxin + NADP+
-
?

Subunits

Subunits Comment Organism
? x * 52000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
AdR
-
Homo sapiens
adrenodoxin reductase
-
Homo sapiens
NADPH-adrenodoxin reductase
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
FAD
-
Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme is the first component in the mitochondrial P450 electron transfer systems. Coexpressed P450, adrenodoxin, and adrenodoxin reductase interact catalytically and allow Escherichia coli to oxidize both cholesterol and vitamin D3 Homo sapiens