Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Bos taurus | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal cortex | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | adrenodoxin stimulates the oxidation of NADPH by 1,4-benzoquinone, catalyzed by NADPH:adrenodoxin reductase. It prevents the enzyme inhibition by NADPH and forms an additional pathway of benzoquinone reduction presumably via reduced adrenodoxin. Adrenodoxin decreases the affinity of the enzyme for NADPH by a limiting factor of 3 and NADP+ decreases the enzyme affinity for adrenodoxin | Bos taurus | ? | - |
? | |
reduced adrenodoxin + NADP | - |
Bos taurus | oxidized adrenodoxin + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
AdR | - |
Bos taurus |
adrenodoxin reductase | - |
Bos taurus |
NADPH:adrenodoxin reductase | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Bos taurus |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme functions in the mitochondrial electron transport chain for cytochrome P450-dependent steroid hydroxylation by donating the electrons to adrenodoxin which further transfers them to cytochromes P450scc or P4511beta | Bos taurus |