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Literature summary for 1.17.99.4 extracted from

  • Patel, B.N.; West, T.P.
    Oxidative catabolism of uracil by Enterobacter aerogenes (1987), FEMS Microbiol. Lett., 40, 33-36.
No PubMed abstract available
Search for more literature for 1.17.99.4

Activating Compound

Activating Compound Comment Organism Structure
methylene blue required as electron acceptor Klebsiella aerogenes

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Klebsiella aerogenes 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
uracil + acceptor Klebsiella aerogenes reaction in two-step oxidative catabolism of uracil in prokaryotes barbiturate + reduced acceptor
-
 ?

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0115
-
-
 Klebsiella aerogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
uracil + acceptor barbiturate, isobarbiturate, 5-methylbarbiturate, 6-methyluracil, dihydrothymine, dihydrouracil, 2-thiouracil, 2-thiothymine, 2-thio-5-methyluracil and cytosine are no substrates Klebsiella aerogenes barbiturate + reduced acceptor
-
 ?
uracil + acceptor reaction in two-step oxidative catabolism of uracil in prokaryotes Klebsiella aerogenes barbiturate + reduced acceptor
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
30
-
 assay at Klebsiella aerogenes

Cofactor

Cofactor Comment Organism Structure
2,6-dichlorophenolindophenol required as electron acceptor, promotes barbiturate formation better than methylene blue Klebsiella aerogenes