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Literature summary for 1.17.7.4 extracted from

  • Hintz, M.; Reichenberg, A.; Altincicek, B.; Bahr, U.; Gschwind, R.M.; Kollas, A.K.; Beck, E.; Wiesner, J.; Eberl, M.; Jomaa, H.
    Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gd T cells in Escherichia coli (2001), FEBS Lett., 509, 317-322.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ Escherichia coli
-
dimethylallyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
r
isopentenyl diphosphate + NAD(P)+ + H2O Escherichia coli biosynthesis of terpenes (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H
-
r
isopentenyl diphosphate + NAD(P)+ + H2O Escherichia coli 2-C-methyl-D-erithritol-4-phosphate pathway (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H
-
r

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
gene lytB
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+
-
Escherichia coli isopentenyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
r
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+
-
Escherichia coli dimethylallyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O
-
r
(E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+
-
Escherichia coli dimethylallyl diphosphate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O dimethylallyl diphosphate is convertable into isopentenyl diphosphate and vice versa r
isopentenyl diphosphate + NAD(P)+ + H2O biosynthesis of terpenes Escherichia coli (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H
-
r
isopentenyl diphosphate + NAD(P)+ + H2O 2-C-methyl-D-erithritol-4-phosphate pathway Escherichia coli (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H
-
r