Inhibitors | Comment | Organism | Structure |
---|---|---|---|
dATP | inhibition of CDP and UDP reduction is reversed by ATP; inhibition of CDP reduction; inhibition of UDP reduction | Escherichia coli | |
GDP | - |
Escherichia coli | |
UDP | - |
Escherichia coli |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0015 | - |
dTTP | positive effector of CDP reduction | Escherichia coli | |
0.07 | - |
ATP | positive effector of CDP reduction | Escherichia coli | |
0.22 | - |
UDP | - |
Escherichia coli |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | subunit B1 requires Mg2+ ions in the 10 mM concentration range for activity | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ribonucleoside diphosphate + reduced thioredoxin | - |
Escherichia coli | 2'-deoxyribonucleoside diphosphate + oxidized thioredoxin + H2O | - |
ir | |
UDP + reduced thioredoxin | - |
Escherichia coli | 2'-deoxy-UDP + oxidized thioredoxin + H2O | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.007 | - |
GDP | competitive vs. CDP | Escherichia coli | |
0.5 | - |
UDP | competitive vs. CDP | Escherichia coli |