Literature summary for 1.17.1.8 extracted from

Rao, A.S.
Regulation of lysine and dipicolinic acid biosynthesis in Bacillus brevis ATCC 10068: significance of derepression of the enzymes during the change from vegetative growth to sporulation (1985), Arch. Microbiol., 141, 143-150.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2,3-dihydrodipicolinate + NAD(P)H	Brevibacillus brevis	highest activity during exponential growth phase	2,3,4,5-tetrahydrodipicolinate + NAD(P)+	-	?
2,3-dihydrodipicolinate + NAD(P)H	Brevibacillus brevis	no regulatory effect of lysine	2,3,4,5-tetrahydrodipicolinate + NAD(P)+	-	?

Organism

Organism	UniProt	Comment	Textmining
Brevibacillus brevis	-	ATCC 10068 and asporogenic mutant BH 7	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
0.01	0.079	depending on growth phase, similar course but lower activity for asporogenic mutant BH 7	Brevibacillus brevis

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2,3-dihydrodipicolinate + NAD(P)H	-	Brevibacillus brevis	2,3,4,5-tetrahydrodipicolinate + NAD(P)+	-	?
2,3-dihydrodipicolinate + NAD(P)H	highest activity during exponential growth phase	Brevibacillus brevis	2,3,4,5-tetrahydrodipicolinate + NAD(P)+	-	?
2,3-dihydrodipicolinate + NAD(P)H	no regulatory effect of lysine	Brevibacillus brevis	2,3,4,5-tetrahydrodipicolinate + NAD(P)+	-	?

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Release 2023.1 (January 2023)