Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.17.1.4 extracted from

  • McManaman, J.L.; Neville, M.C.; Wright, R.M.
    Mouse mammary gland xanthine oxidoreductase: Purification, characterization, and regulation (1999), Arch. Biochem. Biophys., 371, 308-316.
    View publication on PubMed
Search for more literature for 1.17.1.4

Activating Compound

Activating Compound Comment Organism Structure
thiol active compounds conversion of oxidase to dehydrogenase form Mus musculus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
150000
-
 x * 150000, SDS-PAGE Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
xanthine + NAD+ + H2O Mus musculus xanthine oxidase form is the principle major form in fresh mouse milk, dehydrogenase form is the major form in mammary gland, conversion to the dehydrogenase form by thiol active compounds urate + NADH
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, affinity chromatography Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
mammary gland
-
 Mus musculus
-
milk
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
xanthine + 2,6-dichlorophenolindophenol + H2O
-
 Mus musculus urate + ?
-
 ?
xanthine + NAD+ + H2O xanthine oxidase form is the principle major form in fresh mouse milk, dehydrogenase form is the major form in mammary gland, conversion to the dehydrogenase form by thiol active compounds Mus musculus urate + NADH
-
 ?

Subunits

Subunits Comment Organism
? x * 150000, SDS-PAGE Mus musculus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Mus musculus