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Literature summary for 1.17.1.3 extracted from

  • Stafford, H.A.; Lester, H.H.
    Flavan-3-ol biosynthesis. The conversion of (+)-dihydroquercetin and flavan-3,4-cis-diol (leucocyanidin) to (+)-catechin by reductases extracted from cell suspension cultures of douglas fir (1984), Plant Physiol., 76, 184-186.
    View publication on PubMedView publication on EuropePMC
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KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.037
-
 dihydroquercetin pH 7.4 Pseudotsuga menziesii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,3-trans-3,4-cis-leucocyanidin + NADPH Pseudotsuga menziesii proanthocyanidin biosynthesis (2R,3S)-catechin + NADP+ + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudotsuga menziesii
-
 douglas fir
-

Source Tissue

Source Tissue Comment Organism Textmining
cell suspension culture
-
 Pseudotsuga menziesii
-
needle
-
 Pseudotsuga menziesii
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-trans-3,4-cis-leucocyanidin + NADPH enzyme acts mainly on the 3,4-cis rather than the 3,4-trans isomer Pseudotsuga menziesii (2R,3S)-catechin + NADP+ + H2O
-
 ?
2,3-trans-3,4-cis-leucocyanidin + NADPH proanthocyanidin biosynthesis Pseudotsuga menziesii (2R,3S)-catechin + NADP+ + H2O
-
 ?
dihydroquercetin + NADPH double step reduction Pseudotsuga menziesii (2R,3S)-catechin + NADP+ + H2O
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
 Pseudotsuga menziesii

pH Range

pH Minimum pH Maximum Comment Organism
6.4 8 no significant changes between pH 6.4 and pH 8.0 Pseudotsuga menziesii

Cofactor

Cofactor Comment Organism Structure
NADPH dependent Pseudotsuga menziesii