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Literature summary for 1.16.3.1 extracted from
- Antioxidant properties of caeruloplasmin towards iron- and copper-dependent oxygen radical formation (1983), FEBS Lett., 157, 37-40.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | clinical interest relates to its critical role in the diagnosis of Wilson's disease in serum from patients, marked reduction in serum of patients | Homo sapiens |
| medicine | unusual antioxidant property of caeruloplasmin have important implications in vivo for conditions such as rheumatoid joint disease and Wilson's disease, where changes in copper homeostasis, caeruloplasmin and oxygen radicals are known to occur | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Fe2+ + H+ + O2 | Homo sapiens | - |
Fe3+ + H2O | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Fe2+ + H+ + O2 | - |
Homo sapiens | Fe3+ + H2O | - |
? | |
| additional information | caeruloplasmin inhibits lipid peroxidation and deoxyribose degradation stimulated by iron and copper salts | Homo sapiens | ? | - |
? | |
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