Application | Comment | Organism |
---|---|---|
drug development | the enzyme is a target for development of antiangiogenic and antitumour drugs | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tetrathiomolybdate | i.e. ATN-224, choline salt, inhibition leads to antiangiogenic and antitumour effects | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
O2.- + H+ | Mus musculus | enzyme inhibition by tetrathiomolybdate leads to antiangiogenic and antitumour effects in mice | O2 + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
O2.- + H+ | - |
Mus musculus | O2 + H2O2 | - |
? | |
O2.- + H+ | enzyme inhibition by tetrathiomolybdate leads to antiangiogenic and antitumour effects in mice | Mus musculus | O2 + H2O2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
CuZn superoxide dismutase 1 | - |
Mus musculus |
SOD1 | - |
Mus musculus |
superoxide dismutase 1 | - |
Mus musculus |