Crystallization (Comment) | Organism |
---|---|
comparison of native protein and enzyme nitrated at active site residue Y34, no significant change in conformation upon nitration | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
peroxynitrite | almost complete inhibition via nitration of active-site residue Y34, no significant change in conformation upon nitration. Inhibition occurs either through a steric effect of 3-nitrotyrosine 34 that impedes substrate binding or through an electrostatic effect of the nitro group | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P04179 | MnSOD | - |