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Literature summary for 1.15.1.1 extracted from
- The effects of mitochondrial iron homeostasis on cofactor specificity of superoxide dismutase 2 (2006), EMBO J., 25, 1775-1783.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Iron | when mitochondrial iron homeostasis is disrupted, iron accumulates in a reactive form and competes with manganese, inactivating the enzyme. The ability to control the iron pool within mitochondria is critical to maintaining enzyme activity | Saccharomyces cerevisiae |  |
| Manganese | - |
Saccharomyces cerevisiae | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
isoform SOD2 | - |
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Release 2023.1 (January 2023)
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