Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Iron | isoform IsdG is most abundant under iron-depleted conditions. The presence of heme has no effect on the intracellular abundance of IsdG | Staphylococcus lugdunensis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Staphylococcus lugdunensis | A0A133QBY0 | - |
- |
Staphylococcus lugdunensis N920143 | A0A133QBY0 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
protoheme + 4 AH2 + 4 O2 | - |
Staphylococcus lugdunensis | 15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | heme degradation by IsdG results in the release of free iron and the production of the chromophore staphylobilin, i.e. 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin | ? | |
protoheme + 4 AH2 + 4 O2 | - |
Staphylococcus lugdunensis N920143 | 15-oxo-beta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | heme degradation by IsdG results in the release of free iron and the production of the chromophore staphylobilin, i.e. 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin | ? | |
protoheme + 4 AH2 + 4 O2 | - |
Staphylococcus lugdunensis | 5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | heme degradation by IsdG results in the release of free iron and the production of the chromophore staphylobilin, i.e. 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin | ? | |
protoheme + 4 AH2 + 4 O2 | - |
Staphylococcus lugdunensis N920143 | 5-oxo-delta-bilirubin + Fe2+ + CO + 4 A + 4 H2O | heme degradation by IsdG results in the release of free iron and the production of the chromophore staphylobilin, i.e. 5-oxo-delta-bilirubin and 15-oxo-beta-bilirubin | ? |
Synonyms | Comment | Organism |
---|---|---|
isdG | - |
Staphylococcus lugdunensis |
General Information | Comment | Organism |
---|---|---|
physiological function | isoform IsdG-mediated heme catabolism enables the use of heme as a sole source of iron | Staphylococcus lugdunensis |