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Literature summary for 1.14.99.20 extracted from

  • Willingham, A.K.; Matschiner, J.T.
    Changes in phylloquinone epoxidase activity related to prothrombin synthesis and microsomal clotting activity in the rat (1974), Biochem. J., 140, 435-441.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.14.99.20

Inhibitors

Inhibitors Comment Organism Structure
additional information no inhibitors: CO and CN- Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-
microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phylloquinone + electron donor + O2 Rattus norvegicus
-
 2,3-epoxyphylloquinone + oxidized electron + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 rats of a Sprague-Dawley-derived strain, 8-10 weeks old male and female rats
-
Rattus norvegicus
-
 homozygous warfarin-resistent rats
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 maximum enzyme activity requires both the microsomal and the soluble fraction Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information electron donor: NADPH Rattus norvegicus ?
-
 ?
phylloquinone + electron donor + O2
-
 Rattus norvegicus 2,3-epoxyphylloquinone + oxidized electron donor + H2O
-
 ?
phylloquinone + electron donor + O2
-
 Rattus norvegicus 2,3-epoxyphylloquinone + oxidized electron + H2O
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 enzyme assay Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Rattus norvegicus