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Literature summary for 1.14.99.11 extracted from
- Formation of 6beta-hydroxy and 6-keto derivatives of estradiol-16-C14 by mouse liver microsomes (1957), J. Am. Chem. Soc., 79, 1004-1005.
No PubMed abstract available
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Mus musculus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| estradiol-17beta + NADPH + O2 | Mus musculus | estradiol-17beta i.e. estra-1,3,5(10)-triene-3,17beta-diol | 6beta-hydroxyestradiol-17beta + NADP+ + H2O | 6beta-hydroxyestradiol i.e. 6beta-hydroxyestra-1,3,5(10)-triene-3,17beta-diol | ? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| estradiol-17beta + NADPH + O2 | estradiol-17beta i.e. estra-1,3,5(10)-triene-3,17beta-diol | Mus musculus | 6beta-hydroxyestradiol-17beta + NADP+ + H2O | 6beta-hydroxyestradiol i.e. 6beta-hydroxyestra-1,3,5(10)-triene-3,17beta-diol | ? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Mus musculus | |
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Release 2023.1 (January 2023)
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