Cloned (Comment) | Organism |
---|---|
expressed in Nicotiana tabacum leaf and Arabidopsis thaliana seed | Echium plantagineum |
Protein Variants | Comment | Organism |
---|---|---|
D169V/T275A | the mutant has little effect on the D6-desaturation activity of the enzyme | Echium plantagineum |
L14P | the mutant shows dramatically reduced activity compared to the wild type enzyme | Echium plantagineum |
L224S | the mutant shows dramatically reduced activity compared to the wild type enzyme | Echium plantagineum |
L371F | the mutant shows dramatically reduced activity compared to the wild type enzyme | Echium plantagineum |
S205N | the mutant has little effect on the D6-desaturation activity of the enzyme | Echium plantagineum |
S301P | the mutant shows dramatically reduced activity compared to the wild type enzyme | Echium plantagineum |
S391P | the mutant shows dramatically reduced activity compared to the wild type enzyme | Echium plantagineum |
V137A | the mutant shows dramatically reduced activity compared to the wild type enzyme | Echium plantagineum |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ | Echium plantagineum | - |
stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O | - |
? | |
linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ | Echium plantagineum | preferred substrate | gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Echium plantagineum | Q2M488 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ | - |
Echium plantagineum | stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O | - |
? | |
linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ | preferred substrate | Echium plantagineum | gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
D6Des | - |
Echium plantagineum |
DELTA6-desaturase | - |
Echium plantagineum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome b5 | - |
Echium plantagineum |