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Literature summary for 1.14.19.47 extracted from

  • Marzo, I.; Alava, M.A.; Pineiro, A.; Naval, J.
    Biosynthesis of docosahexaenoic acid in human cells: Evidence that two different DELTA 6-desaturase activities may exist (1996), Biochim. Biophys. Acta, 1301, 263-272.
    View publication on PubMed
Search for more literature for 1.14.19.47

Inhibitors

Inhibitors Comment Organism Structure
trans-9,12-linoleic acid potent inhibitor Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Homo sapiens
-
 stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+ Homo sapiens
-
 gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
JURKAT cell
-
 Homo sapiens
-
retinoblastoma cell
-
 Homo sapiens
-
Y-79 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-linolenoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Homo sapiens stearidonoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?
linoleoyl-[glycerolipid] + ferrocytochrome b5 + O2 + H+
-
 Homo sapiens gamma-linolenoyl-[glycerolipid] + ferricytochrome b5 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
DELTA 6-desaturase
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
cytochrome b5
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens neuronal differentiation of Y-79 cells causes a great increase in enzyme activity up