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Literature summary for 1.14.19.3 extracted from

  • Chuang, L.T.; Thurmond, J.M.; Liu, J.W.; Kirchner, S.J.; Mukerji, P.; Bray, T.M.; Huang, Y.S.
    Effect of conjugated linoleic acid on fungal DELTA6-desaturase activity in a transformed yeast system (2001), Lipids, 36, 139-143.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
Saccharomyces cerevisiae transformed with fungal DELTA6-desaturase gene Mortierella alpina

Inhibitors

Inhibitors Comment Organism Structure
conjugated linoleic acid all CLA isomers inhibits significantly the activity of DELTA6-desaturase, the c9,t11 isomer is the most potent inhibitor Mortierella alpina

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
linoleic acid + AH2 + O2 Mortierella alpina
-
gamma-linolenic acid + A + H2O
-
?

Organism

Organism UniProt Comment Textmining
Mortierella alpina
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
linoleic acid + AH2 + O2
-
Mortierella alpina gamma-linolenic acid + A + H2O
-
?
octadeca-9,12-dienoic acid + AH2 + O2
-
Mortierella alpina gamma-linolenic acid + A + H2O
-
?