Organism | UniProt | Comment | Textmining |
---|---|---|---|
Candida albicans | O93875 | isolates C43, C655, C673, and C410 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
14-methylfecosterol + ferrocytochrome b5 + O2 + H+ | - |
Candida albicans | 14-methylergosta-5,8,24(28)-trien-3beta-ol + ferricytochrome b5 + H2O | - |
? | |
ergosta-7,22-dien-3beta-ol + ferrocytochrome b5 + O2 + H+ | - |
Candida albicans | ergosterol + ferricytochrome b5 + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Erg3p | - |
Candida albicans |
sterol DELTA5,6-desaturase | - |
Candida albicans |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome b5 | - |
Candida albicans |
General Information | Comment | Organism |
---|---|---|
malfunction | inactivation of sterol DELTA5,6-desaturase attenuates virulence in Candida albicans | Candida albicans |
metabolism | the enzyme is involved in ergosterol synthesis | Candida albicans |