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Literature summary for 1.14.19.1 extracted from

  • Macdonald, M.L.; Bissada, N.; Vallance, B.A.; Hayden, M.R.
    Absence of stearoyl-CoA desaturase-1 does not promote DSS-induced acute colitis (2009), Biochim. Biophys. Acta, 1791, 1166-1172.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
stearoyl-CoA + NADH + H+ + O2
-
Mus musculus oleoyl-CoA + NAD+ + H2O
-
?

Synonyms

Synonyms Comment Organism
SCD1
-
Mus musculus
stearoyl-CoA desaturase-1
-
Mus musculus

Cofactor

Cofactor Comment Organism Structure
NADH
-
Mus musculus

General Information

General Information Comment Organism
physiological function absence of stearoyl-CoA desaturase-1 leads to chronic inflammation of the skin and increased susceptibility to atherosclerosis, while also increasing plasma inflammatory markers, but does not promote dextran sulfate sodium-induced acute colitis Mus musculus