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Literature summary for 1.14.19.1 extracted from

  • Mar-Heyming, R.; Miyazaki, M.; Weissglas-Volkov, D.; Kolaitis, N.A.; Sadaat, N.; Plaisier, C.; Pajukanta, P.; Cantor, R.M.; de Bruin, T.W.; Ntambi, J.M.; Lusis, A.J.
    Association of stearoyl-CoA desaturase 1 activity with familial combined hyperlipidemia (2008), Arterioscler. Thromb. Vasc. Biol., 28, 1193-1199.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ Homo sapiens rate-limiting enzyme involved in the synthesis of monounsaturated fatty acids, it is also involved in familial combined hyperlipidemia, fatty acid desaturation index, overview oleoyl-CoA + ferricytochrome b5 + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
stearoyl-CoA + ferrocytochrome b5 + O2 + H+
-
 Homo sapiens oleoyl-CoA + ferricytochrome b5 + H2O
-
 ?
stearoyl-CoA + ferrocytochrome b5 + O2 + H+ rate-limiting enzyme involved in the synthesis of monounsaturated fatty acids, it is also involved in familial combined hyperlipidemia, fatty acid desaturation index, overview Homo sapiens oleoyl-CoA + ferricytochrome b5 + H2O
-
 ?

Synonyms

Synonyms Comment Organism
SCD1
-
 Homo sapiens
stearoyl-CoA desaturase 1
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
ferrocytochrome b5
-
 Homo sapiens