Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A-549 cell | lung adenocarcinoma cells | Homo sapiens | - |
lung fibroblast | normal lung fibroblasts WI38 and the derived SV40-tranformed strain cells SV40-WI38, SCD protein content 3.3fold increased in SV40-WI38 cells compared to WI38 cells | Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
incubation of A-549 cells with 25 microM C6-ceramide for 6 h and 24 h leads to a 45% and 25% decrease in enzyme activity | Homo sapiens |
additional information | - |
induction of apoptosis with 40 microM etoposide leads to a 20% decrease in enzyme activity in SV40-transformed WI38 fibroblasts compared to normal WI38 fibroblasts, which are resistant to etoposide-induced apoptosis | Homo sapiens |
additional information | - |
SV40-transformed WI38 fibroblasts exhibit a 2.2fold higher enzyme activity compared to normal WI38 cells | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | enzyme activity measured by conversion of 14C-stearic acid to 14C-oleic acid, reverse-phase HPLC | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCD | - |
Homo sapiens |