Protein Variants | Comment | Organism |
---|---|---|
additional information | FA2H lacking the N-terminal cytochrome b5 domain has little activity | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | protein contains four potential transmembrane domains | Homo sapiens | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q7L5A8 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Homo sapiens | - |
colon | - |
Homo sapiens | - |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
cytochrome b5 | FA2H protein contains an N-terminal cytochrome b5 domain | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | COS7 cells expressing human FA2H contain 3-20fold higher levels of 2-hydroxyceramides (C16, C18, C24, and C24:1) and 2-hydroxy fatty acids compared with control cells | Homo sapiens |