Literature summary for 1.14.18.5 extracted from

Ternes, P.; Franke, S.; Zaehringer, U.; Sperling, P.; Heinz, E.
Identification and characterization of a sphingolipid delta 4-desaturase family (2002), J. Biol. Chem., 277, 25512-25518.

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Organism

Organism	UniProt	Comment	Textmining
Mus musculus	Q8R2F2	bifunctional sphingolipid delta(4)-desaturase/C4-monooxygenase	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
sphinganine ceramide + 2 ferrocytochrome b5 + O2 + 2 H+	-	Mus musculus	4-hydroxysphinganine ceramide + 2 ferricytochrome b5 + H2O	plus (E)-sphing-4-enine ceramide, the (E)-sphing-4-enine/4-hydroxysphinganine ratio is 2.5:1	?

Synonyms

Synonyms	Comment	Organism
DES2	-	Mus musculus
sphingolipid delta(4)-desaturase/C4-monooxygenase	-	Mus musculus

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Release 2023.1 (January 2023)