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Literature summary for 1.14.18.3 extracted from

  • Lieberman, R.L.; Kondapalli, K.C.; Shrestha, D.B.; Hakemian, A.S.; Smith, S.M.; Telser, J.; Kuzelka, J.; Gupta, R.; Borovik, A.S.; Lippard, S.J.; Hoffman, B.M.; Rosenzweig, A.C.; Stemmler, T.L.
    Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy (2006), Inorg. Chem., 45, 8372-8381.
    View publication on PubMedView publication on EuropePMC

Metals/Ions

Metals/Ions Comment Organism Structure
Cu2+ the enzyme contains a mononuclear copper center and a dinuclear copper center, Cu-Cu interaction occurs in all redox forms of the enzyme, usage of mixed-valent dinuclear Cu model compounds, [tris{(N'-tert-butylureaylato)-N-ethyl}aminatocopper(II)]2BF4, and [N-tert-butylurealylato-{2-(dimethylamino)ethyl}aminatocopper(II)]2BF4, which are blue, and purple samples of [Cu2(m-xylylenediaminebis(Kemp’s triacid imide))(my-OTf)(THF)2], and [Cu2(m-xylylenediaminebis(Kemp’s triacid imide))(my-O2CCF3)(THF)2], EXAFS and Fourier transformation analysis, detailed interaction analysis, overview Methylococcus capsulatus
additional information analysis of the oxidation states and coordination environments of the pMMO metal centers, overview Methylococcus capsulatus
Zn2+ the enzyme contains a nonphysiological mononuclear zinc center Methylococcus capsulatus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
methane + reduced acceptor + H* + O2 Methylococcus capsulatus
-
methanol + acceptor + H2O
-
?
methane + reduced acceptor + H* + O2 Methylococcus capsulatus Bath
-
methanol + acceptor + H2O
-
?

Organism

Organism UniProt Comment Textmining
Methylococcus capsulatus
-
-
-
Methylococcus capsulatus Bath
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
methane + reduced acceptor + H* + O2
-
Methylococcus capsulatus methanol + acceptor + H2O
-
?
methane + reduced acceptor + H* + O2
-
Methylococcus capsulatus Bath methanol + acceptor + H2O
-
?

Synonyms

Synonyms Comment Organism
particulate methane monooxygenase
-
Methylococcus capsulatus
pMMO
-
Methylococcus capsulatus

Cofactor

Cofactor Comment Organism Structure
NADH
-
Methylococcus capsulatus