Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-picolyl heptyl amine | - |
Agaricus bisporus | |
alpha-picolyl nonyl amine | - |
Agaricus bisporus | |
alpha-picolyl pentyl amine | - |
Agaricus bisporus | |
alpha-picolyl propyl amine | - |
Agaricus bisporus | |
beta-picolyl heptyl amine | uncompetitive inhibition of monophenolase and diphenolase activities | Agaricus bisporus | |
beta-picolyl nonyl amine | - |
Agaricus bisporus | |
beta-picolyl pentyl amine | uncompetitive inhibition of monophenolase and diphenolase activities | Agaricus bisporus | |
beta-picolyl propyl amine | uncompetitive inhibition of monophenolase and diphenolase activities | Agaricus bisporus | |
gamma-picolyl heptyl amine | uncompetitive inhibition of monophenolase activity and mixed-type inhibition of diphenolase activity | Agaricus bisporus | |
gamma-picolyl nonyl amine | - |
Agaricus bisporus | |
gamma-picolyl pentyl amine | uncompetitive inhibition of monophenolase activity and mixed-type inhibition of diphenolase activity | Agaricus bisporus | |
gamma-picolyl propyl amine | uncompetitive inhibition of monophenolase activity and mixed-type inhibition of diphenolase activity | Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-DOPA + O2 | o-diphenolase activity | Agaricus bisporus | dopaquinone + H2O | - |
? | |
L-tyrosine + O2 | o-monophenolase activity | Agaricus bisporus | L-DOPA + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | - |
Agaricus bisporus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
18 | - |
gamma-picolyl heptyl amine | in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | |
20 | - |
gamma-picolyl pentyl amine | in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | |
23 | - |
gamma-picolyl propyl amine | in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
4.2 | - |
in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | gamma-picolyl pentyl amine | |
5.8 | - |
in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | gamma-picolyl propyl amine | |
6.8 | - |
- |
Agaricus bisporus | gamma-picolyl heptyl amine | |
9.5 | - |
in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | beta-picolyl heptyl amine | |
12 | - |
IC50 above 12 mM, in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | alpha-picolyl propyl amine | |
12 | - |
IC50 above 12 mM, in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | alpha-picolyl pentyl amine | |
12 | - |
IC50 above 12 mM, in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | alpha-picolyl heptyl amine | |
12 | - |
in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | beta-picolyl propyl amine | |
12 | - |
in 0.1 M phosphate buffer (pH 6.5) | Agaricus bisporus | beta-picolyl pentyl amine |