Inhibitors | Comment | Organism | Structure |
---|---|---|---|
3'',4''-dihydroglabridin | 100% inhibition at 0.33 mg/ml | Agaricus bisporus | |
glabridin | 99.8% inhibition at 0.33 mg/ml | Agaricus bisporus | |
kojic acid | 76.41% inhibition at 0.33 mg/ml | Agaricus bisporus | |
additional information | not inhibited by glabridin diacetate, glabridin dihexanoate, glabridin didecanoate, glabridin dipalmitate, and glabridin distearate | Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + L-dopa + O2 | - |
Agaricus bisporus | L-dopa + dopaquinone + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | - |
Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0114 | - |
in 20 mM phosphate buffer (pH 6.8), at 25°C | Agaricus bisporus | 3'',4''-dihydroglabridin | |
0.01476 | - |
in 20 mM phosphate buffer (pH 6.8), at 25°C | Agaricus bisporus | kojic acid | |
0.01858 | - |
in 20 mM phosphate buffer (pH 6.8), at 25°C | Agaricus bisporus | glabridin |