Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2'-(3,4-dihydroxyphenyl)-3',5,5',7,7'-pentahydroxy-2-(4-hydroxyphenyl)-2,2',3,3',4a,8a-hexahydro-4H,4'H-3,8'-bichromene-4,4'-dione | most potent inhibitor | Agaricus bisporus | |
3',5,5',7,7'-pentahydroxy-2,2'-bis(4-hydroxyphenyl)-2,2',3,3',4a,8a-hexahydro-4H,4'H-3,8'-bichromene-4,4'-dione | - |
Agaricus bisporus | |
5,5',7,7'-tetrahydroxy-2,2'-bis(4-hydroxyphenyl)-2,2',3,3',4a,8a-hexahydro-4H,4'H-3,8'-bichromene-4,4'-dione | - |
Agaricus bisporus | |
5,5',7-trihydroxy-2,2'-bis(4-hydroxyphenyl)-4,4'-dioxo-3,3',4,4',4a,8a-hexahydro-2H,2'H-3,8'-bichromen-7'-yl D-glucopyranoside | tyrosinase inhibitor isolated from extracts of the seeds of Garcinia kola | Agaricus bisporus | |
kojic acid | - |
Agaricus bisporus | |
kolaflavonone | - |
Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Agaricus bisporus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-dopa + 1/2 O2 | - |
Agaricus bisporus | L-dopaquinone + H2O | - |
? | |
L-tyrosine + O2 + AH2 | - |
Agaricus bisporus | L-dopa + H2O + A | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | rate-limiting enzyme in melanin synthesis | Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.13 | - |
- |
Agaricus bisporus | kojic acid | |
0.582 | - |
- |
Agaricus bisporus | 2'-(3,4-dihydroxyphenyl)-3',5,5',7,7'-pentahydroxy-2-(4-hydroxyphenyl)-2,2',3,3',4a,8a-hexahydro-4H,4'H-3,8'-bichromene-4,4'-dione |