Literature summary for 1.14.18.1 extracted from

Masuda, T.; Odaka, Y.; Ogawa, N.; Nakamoto, K.; Kuninaga, H.
Identification of geranic acid, a tyrosinase inhibitor in lemongrass (Cymbopogon citratus) (2008), J. Agric. Food Chem., 56, 597-601.

Search for more literature for 1.14.18.1

Inhibitors

Inhibitors	Comment	Organism	Structure
3-methylcrotonic acid	-	Agaricus bisporus
angelic acid	-	Agaricus bisporus
crotonic acid	-	Agaricus bisporus
farnesic acid	-	Agaricus bisporus
geranial	-	Agaricus bisporus
geranic acid	in lemongrass (Cymbopogon citratus)	Agaricus bisporus
geranic acid ethyl amide	-	Agaricus bisporus
geranic acid ethyl ester	-	Agaricus bisporus
geranic acid ethylene glycol ester	-	Agaricus bisporus
geraniol	-	Agaricus bisporus
isovaleric acid	-	Agaricus bisporus
Methacrylic acid	-	Agaricus bisporus
tiglic acid	-	Agaricus bisporus
trans-geranic acid	-	Agaricus bisporus

Organism

Organism	UniProt	Comment	Textmining
Agaricus bisporus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Agaricus bisporus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-dopa + 1/2 O2	-	Agaricus bisporus	L-dopaquinone + H2O	-	?

Synonyms

Synonyms	Comment	Organism
tyrosinase	-	Agaricus bisporus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.11	-	-	Agaricus bisporus	farnesic acid
0.14	-	isomer 1	Agaricus bisporus	trans-geranic acid
1.62	-	-	Agaricus bisporus	geranial
1.7	-	-	Agaricus bisporus	3-methylcrotonic acid
2.3	-	isomer 2	Agaricus bisporus	trans-geranic acid

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Release 2023.1 (January 2023)