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Literature summary for 1.14.18.1 extracted from

  • Morimura, K.; Yamazaki, C.; Hattori, Y.; Makabe, H.; Kamo, T.; Hirota, M.
    A tyrosinase inhibitor, Daedalin A, from mycelial culture of Daedalea dickinsii (2007), Biosci. Biotechnol. Biochem., 71, 2837-2840.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
arbutin
-
Agaricus bisporus
daedalin A (2R)-6-hydroxy-2-hydroxymethyl-2-methyl-2H-chromene from mycelial culture of Daedalea dickinsii Agaricus bisporus

Organism

Organism UniProt Comment Textmining
Agaricus bisporus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Agaricus bisporus

Source Tissue

Source Tissue Comment Organism Textmining
commercial preparation
-
Agaricus bisporus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
aqueous solution of mushroom tyrosinase (1000 U/ml) Agaricus bisporus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tyrosine + O2 + AH2
-
Agaricus bisporus L-dopa + H2O + A
-
?

Synonyms

Synonyms Comment Organism
tyrosinase
-
Agaricus bisporus

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
additional information
-
daedalin A also shows 1,1-diphenyl-2-picrylhydrazyl scavenging activity (IC50: 16.9 microM) and superoxide anion scavenging activity (IC50: 28.5 microM) Agaricus bisporus additional information
0.194
-
-
Agaricus bisporus daedalin A
0.672
-
daedalin A is 3times more potent than arbutin Agaricus bisporus arbutin