Cloned (Comment) | Organism |
---|---|
expression of wild-type, N86Q, N111Q, N337Q, N371Q and several double and triple mutant enzymes derived from this single mutants in CHO cells | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
N111Q | mutation in potential N-glycosylation site, 95% of wild-type L-dopa oxidase activity | Homo sapiens |
N111Q/N337Q | mutations in potential N-glycosylation site, 95% of wild-type L-dopa oxidase activity | Homo sapiens |
N111Q/N337Q/N371Q | mutations in potential N-glycosylation site, no L-dopa oxidase activity | Homo sapiens |
N111Q/N371Q | mutations in potential N-glycosylation site, 59% of wild-type L-dopa oxidase activity | Homo sapiens |
N337Q | mutation in potential N-glycosylation site, 93% of wild-type L-dopa oxidase activity | Homo sapiens |
N337Q/N3711Q | mutations in potential N-glycosylation site, 37% of wild-type L-dopa oxidase activity | Homo sapiens |
N371Q | mutation in potential N-glycosylation site, 64% of wild-type L-dopa oxidase activity | Homo sapiens |
N86Q | mutation in potential N-glycosylation site, 70% of wild-type L-dopa oxidase activity | Homo sapiens |
N86Q/N111Q | mutations in potential N-glycosylation site, 68% of wild-type L-dopa oxidase activity | Homo sapiens |
N86Q/N111Q/N337Q | mutations in potential N-glycosylation site, no L-dopa oxidase activity | Homo sapiens |
N86Q/N111Q/N337Q/N371Q | mutations in potential N-glycosylation site, no L-dopa oxidase activity | Homo sapiens |
N86Q/N111Q/N371Q | mutations in potential N-glycosylation site, no L-dopa oxidase activity | Homo sapiens |
N86Q/N337Q | mutations in potential N-glycosylation site, 35% of wild-type L-dopa oxidase activity | Homo sapiens |
N86Q/N337Q/N371Q | mutations in potential N-glycosylation site, no L-dopa oxidase activity | Homo sapiens |
N86Q/N371Q | mutations in potential N-glycosylation site, 30% of wild-type L-dopa oxidase activity, contains at least 3 times less copper than wild-type | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |