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Literature summary for 1.14.18.1 extracted from
- Mammalian monophenol monooxygenase (tyrosinase): purification, properties, and reactions catalyzed (1987), Methods Enzymol., 142, 154-165.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-3,4-dihydroxyphenylalanine + 1/2 O2 | Mammalia | - |
L-dopaquinone + H2O | - |
? |  |
| L-3,4-dihydroxyphenylalanine + 1/2 O2 | Mus musculus | - |
L-dopaquinone + H2O | - |
? | |
| L-tyrosine + O2 + AH2 | Mammalia | - |
L-3,4-dihydroxyphenylalanine + H2O + A | - |
? | |
| L-tyrosine + O2 + AH2 | Mus musculus | - |
L-3,4-dihydroxyphenylalanine + H2O + A | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mammalia | - |
- |
- |
| Mus musculus | - |
B16 melanoma cells | - |
| Mus musculus | - |
isoenzymes T1, T2, T3 and T4 | - |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| glycoprotein | - |
Mammalia |
| glycoprotein | - |
Mus musculus |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Mammalia |
| ammonium sulfate, S-300 chromatography, preparative PAGE | Mus musculus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| melanoma cell | - |
Mammalia | - |
| melanoma cell | - |
Mus musculus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
assay methods | Mammalia |
| 45 | - |
- |
Mammalia |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylcatechol + O2 | - |
Mammalia | 4-methyl-o-benzoquinone + H2O | - |
? | |
| 4-methylcatechol + O2 | - |
Mus musculus | 4-methyl-o-benzoquinone + H2O | - |
? | |
| L-3,4-dihydroxyphenylalanine + 1/2 O2 | - |
Mammalia | L-dopaquinone + H2O | - |
? | |
| L-3,4-dihydroxyphenylalanine + 1/2 O2 | - |
Mus musculus | L-dopaquinone + H2O | - |
? | |
| L-tyrosine + O2 + AH2 | - |
Mammalia | L-3,4-dihydroxyphenylalanine + H2O + A | - |
? | |
| L-tyrosine + O2 + AH2 | - |
Mus musculus | L-3,4-dihydroxyphenylalanine + H2O + A | - |
? | |
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