KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.5 | 2 | tyramine | enzyme from serum of 5-weeks-old rats, at 37°C, pH not specified in the publication | Rattus norvegicus | |
0.79 | - |
tyramine | enzyme from serum of 2-weeks-old rats, at 37°C, pH not specified in the publication | Rattus norvegicus | |
0.92 | - |
tyramine | enzyme from serum of 8-weeks-old rats, at 37°C, pH not specified in the publication | Rattus norvegicus | |
1.22 | - |
tyramine | enzyme from serum of 1-weeks-old rats, at 37°C, pH not specified in the publication | Rattus norvegicus | |
1.37 | - |
tyramine | enzyme from serum of 12-weeks-old rats, at 37°C, pH not specified in the publication | Rattus norvegicus | |
1.6 | - |
tyramine | enzyme from serum of 15-weeks-old rats, at 37°C, pH not specified in the publication | Rattus norvegicus | |
2.1 | - |
tyramine | enzyme from serum of 27-weeks-old rats, at 37°C, pH not specified in the publication | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
dopamine + ascorbate + O2 | Rattus norvegicus | - |
norepinephrine + dehydroascorbate + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Rattus norvegicus | - |
brain | highest activity | Rattus norvegicus | - |
brain stem | - |
Rattus norvegicus | - |
caudate nucleus | - |
Rattus norvegicus | - |
cerebellum | - |
Rattus norvegicus | - |
cerebral cortex | - |
Rattus norvegicus | - |
heart | - |
Rattus norvegicus | - |
hypothalamus | - |
Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
lung | - |
Rattus norvegicus | - |
midbrain colliculus | - |
Rattus norvegicus | - |
pancreas | - |
Rattus norvegicus | - |
serum | - |
Rattus norvegicus | - |
small intestine | - |
Rattus norvegicus | - |
spleen | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
dopamine + ascorbate + O2 | - |
Rattus norvegicus | norepinephrine + dehydroascorbate + H2O | - |
? | |
tyramine + ascorbate + O2 | - |
Rattus norvegicus | octopamine + dehydroascorbate + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3,4-dihydroxy-phenylethylamine, ascorbate: oxygen oxidoreductase (3-hydroxylating) | - |
Rattus norvegicus |
DBH | - |
Rattus norvegicus |
dopamine-beta-hydroxylase | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | enzyme expression is highest in 5-weeks-old rats | up |