Cloned (Comment) | Organism |
---|---|
expressed in CHO cell, expressed in Xenopus laevis oocyte, GFP fusion protein expressed in CHO cell, 6x myc tag version expressed in CHO-K1 cell | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | mutation of each of 8 conserved His residues (to alanine) which are all essential for activity | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,10-phenanthroline | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00258 | - |
tetrahydrobiopterin | measured in CHO cells after transfection, pH not specified in the publication, 37°C | Homo sapiens | |
0.011 | - |
1-O-pyrenedecyl-sn-glycerol | measured in CHO cells after transfection, pH not specified in the publication, 37°C | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-O-pyrenedecyl-sn-glycerol + tetrahydrobiopterin + O2 | - |
Homo sapiens | glycerol + pyrenedecanal + 6,7[8H]-dihydrobiopterin + H2O | - |
? | |
alkylglycerol + tetrahydrobiopterin + O2 | - |
Homo sapiens | glycerol + fatty aldehyde + 6,7[8H]-dihydrobiopterin + H2O | after rapid decay of the resulting unstable primary product (hemiacetal) | ? |
Synonyms | Comment | Organism |
---|---|---|
alkylglycerol monooxygenase | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00139 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 1,10-phenanthroline |